Effects of Different Remineralization Agents on Molar Incisor Hypomineralization Defects: a Randomized Clinical Study
Randomized Clinical Trial to Evaluate the Effectiveness of Three Remineralizing Agents on Mineral Density in Permanent Teeth and Molars With Molar Incisor Hypomineralization
Universidad Nacional Autonoma de Mexico
100 participants
Mar 1, 2024
INTERVENTIONAL
Conditions
Summary
The aim of this study was to present a comparative evaluation of the long-term efficacy of fluoride varnish( Flúor protector), Clinpro™ White Varnish and pastes containing CPP-ACP in the remineralization of creamy-white and yellow brown defects in incisors and permanent first molars with Molar Incisor Hypomineralization (MIH) in schoolchildren 6-12 years-old in Mexico.
Eligibility
Inclusion Criteria5
- Children between 6 to 12 years
- They live in the selected study area
- Have at least one permanent incisor or molar with mild or moderate MIH (creamy white and/or yellow or brown opacities)
- That their parents authorize participation in the study through informed consent.
- No proven or suspected allergy and/or sensitivity to milk protein, as it is a component of the CPP-ACP product.
Exclusion Criteria4
- Defects in enamel development related to syndromes, dental fluorosis, amelogenesis imperfecta, dentinogenesis imperfecta.
- Presence of orthodontic appliances.
- Teeth with MIH with restorations, or severe MIH (affected enamel develops post-eruptive enamel breakdown), or carious lesions classified as score >0 according to the ICDAS.
- Children who do not show cooperation in the use of remineralizing agents.
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Interventions
Application of remineralizing agents on teeth and molars with MIH during 24 months of follow-up.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06362681