RecruitingNot ApplicableNCT06363071

APA and PAS Training for Gait Initiation in Parkinson's Disease

Gait-initiation Related APA Training in Individuals With Parkinson Disease -Explicit Training and Paired Associative Stimulation(PAS) Priming

Sponsor

Chang Gung University

Enrollment

100 participants

Start Date

Jun 13, 2022

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

Our research focused on understanding the interplay between brain excitability and balance function in patients with Parkinson's disease (PD), alongside evaluating effective physical therapy methods. It highlights the prevalence of non-motor disorders and cognitive impairments among PD patients, including balance and postural issues, cognitive function decline, and gait instability. Additionally, it notes that PD patients exhibit abnormal electrophysiological responses, indicating altered central excitability.

Eligibility

Min Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This study looks at how two different types of movement training — Anticipatory Postural Adjustments (APA) and Protective Action Strategies (PAS) — affect the ability to start walking in people with Parkinson's disease, compared to healthy adults. The goal is to improve balance and reduce falls. **You may be eligible if (Parkinson's group)...** - You have a clinical diagnosis of Parkinson's disease **You may be eligible if (healthy control group)...** - You are a healthy adult with no significant leg or bone conditions **You may NOT be eligible if...** - You have musculoskeletal injuries affecting your legs - You have osteoporosis (brittle bones) - You have Parkinson's disease and also have other neurological conditions (nerve or brain disorders) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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