APA and PAS Training for Gait Initiation in Parkinson's Disease
Gait-initiation Related APA Training in Individuals With Parkinson Disease -Explicit Training and Paired Associative Stimulation(PAS) Priming
Chang Gung University
100 participants
Jun 13, 2022
INTERVENTIONAL
Conditions
Summary
Our research focused on understanding the interplay between brain excitability and balance function in patients with Parkinson's disease (PD), alongside evaluating effective physical therapy methods. It highlights the prevalence of non-motor disorders and cognitive impairments among PD patients, including balance and postural issues, cognitive function decline, and gait instability. Additionally, it notes that PD patients exhibit abnormal electrophysiological responses, indicating altered central excitability.
Eligibility
Inclusion Criteria2
- Health subjects:
- \- Clinical diagnosis of Parkinson disease.
Exclusion Criteria6
- Musculoskeletal injuries on legs.
- Osteoporosis.
- PD subjects:
- Musculoskeletal injuries on legs
- Osteoporosis.
- Any peripheral or central nervous system injury or disease patients.
Interventions
Use COP trajectory to train weight shift on force plate. To give APA visual feedback for subjects after weight shift training.
Use TMS combine ES to stimulate TA nerve and M1 cortical
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06363071