A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)
A Model Based on Resected Normal Liver Parenchymal Volume（RNLV）to Predict the Risk of Post-Hepatectomy Liver Failure (PHLF)
National Natural Science Foundation of China
1,600 participants
Dec 1, 2022
OBSERVATIONAL
Conditions
Summary
The post-hepatotectomy liver failure (PHLF) is still the most worrisome complication of hepatic resection. Surgeons have always been making efforts to preoperatively predict PHLF using kinds of techniques, scoring systems, and variables. The investigators of this study tried to create an individual predictive model based on the variable, resected normal parenchymal volume (RNLV), then assessing the performance and value of the model in clinical practice.
Eligibility
Inclusion Criteria3
- selective hepatectomies;
- histologically confirmed as HCC and ICC
- complete and accessible data
Exclusion Criteria6
- any history of Associated Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS)
- any history of portal vein embolism (PVE)
- any history of tumor rupture
- emergency surgery
- pathologically diagnosed with neither HCC nor ICC
- concomitant resection of gastrointestinal organs, spleenectomy or other organs
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Our study respectively defined the PHLF according to the 50-50 criteria and the ISGLS criteria in literature review.
Locations(3)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06366048