Liver Failure Clinical Trials

3 recruiting

Frequently Asked Questions

Common questions about Liver Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting
Phase 1

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

Advanced or Metastatic Solid TumorLiver Failure
Gilead Sciences30 enrolled13 locationsNCT04617522
Recruiting
Not Applicable

Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and Sepsis

SepsisAcute-On-Chronic Liver Failure
Third Affiliated Hospital, Sun Yat-Sen University60 enrolled1 locationNCT06562803
Recruiting

CytOSorb TreatMent Of Critically Ill PatientS Registry

SepsisLiver Transplant; ComplicationsPancreatitis+15 more
CytoSorbents, Inc3,000 enrolled28 locationsNCT05146336
Recruiting
Phase 3

Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas)

Kidney FailureLiver Failure, ChronicKidney-Pancreas Failure
Dr. F. Köhler Chemie GmbH362 enrolled4 locationsNCT03627013
Recruiting
Phase 1Phase 2

CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection

Liver CancerLiver MetastasesLiver Cirrhosis+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053488
Recruiting

Study About Hepatic Toxins Kinetic and Evaluation of Organ Damage in Acute on Chronic Liver Failure (ACLF) Patients

Acute on Chronic Liver Failure (ACLF)
IRCCS Azienda Ospedaliero-Universitaria di Bologna40 enrolled3 locationsNCT06837766
Recruiting
Not Applicable

Efficacy and Safety of ALSS Treatment for ICIs-LF in Patients With HCC

Hepatocellular CarcinomaImmune-Mediated HepatitisLiver Failure
Third Affiliated Hospital, Sun Yat-Sen University60 enrolled1 locationNCT05484908
Recruiting

Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease

SurgeryLiver CirrhosisAcute-On-Chronic Liver Failure+2 more
University Hospital, Bonn200 enrolled1 locationNCT04578301