RecruitingPhase 2NCT06372249

A Clinical Trial of Soluble Fiber for Asthma

A Phase ll Randomized Controlled Trial of Soluble Fiber for Asthma


Sponsor

Phoenix Children's Hospital

Enrollment

105 participants

Start Date

Nov 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Randomized controlled trial of soluble fiber (Fruitafit Inulin). Participants will complete an ASA 24 dietary recall questionnaire to access their fiber intake. If eligible for the study, participants will be supplemented to their target fiber dosage with either soluble fiber (Fruitafit Inulin) or placebo. Collection of blood serum, fecal samples, and nasal wash will aid in analyzing the microbes present in one's gut and how fiber and diet may impact it. Thus, allowing researchers to better understand the pathways that may connect diet and asthma and if it is possible to improve asthma by altering one's diet.


Eligibility

Min Age: 6 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is testing whether adding soluble fiber supplements to the diet can help reduce inflammation and improve asthma symptoms in children with allergic asthma. The gut-lung connection is a growing area of research, and fiber may help calm the immune response. **You may be eligible if...** - Your child is between 6 and 17 years old - They have been diagnosed with asthma in the last 2 years - They test positive for environmental allergies or have elevated exhaled nitric oxide (a sign of lung inflammation) - No emergency room visit for asthma in the past month **You may NOT be eligible if...** - Your child has cystic fibrosis or bronchiectasis - A change in their asthma medications is planned in the next 4–6 weeks - Their current diet is already very low in fiber - A sibling is already enrolled in the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGInulin

Soluble tapioca starch from Ingredion.


Locations(1)

Phoenix Children's

Phoenix, Arizona, United States

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NCT06372249


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