Resistance Training and Corticospinal Excitability in Multiple Sclerosis

This study is looking at whether resistance (strength) training can improve the brain-to-muscle signaling pathways in people with Multiple Sclerosis (MS) who have walking difficulties. Researchers will measure changes in corticospinal excitability — how well the brain communicates with muscles — before and after a resistance training program. **You may be eligible if...** - You are 18 or older with a confirmed MS diagnosis - You have walking difficulties related to MS - You can travel independently to training and testing sessions - You have not done regular structured resistance training (2+ sessions/week) in the past 3 months **You may NOT be eligible if...** - You are pregnant - You have a pacemaker or metal implants - You have uncontrolled high blood pressure - You had an MS relapse in the last 2 months - You have other neurological conditions affecting the nervous system Talk to your doctor to see if this trial is right for you.