RecruitingNot ApplicableNCT06374641

The Effects of a Novel Mitochondrial Substrate Supplement on Exercise Performance and Cognitive Function


Sponsor

University of Exeter

Enrollment

40 participants

Start Date

Mar 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to compare the effects of taking a new supplement for 16 days on cognitive function and exercise performance, compared to a placebo (a supplement that looks and tastes the same, but doesn't have the same ingredients) in 40 healthy individuals - 20 young individuals (aged 18-30) and 20 older individuals (aged 50-65). The main questions it aims to answer are: * If taking the supplement for 16 days improves exercise performance, or the speed with which the body responds to the commencement of exercise. * If taking the supplement improves cognitive function. Participants will visit the lab on 5 separate occasions to: * complete some cognitive tests * complete exercise performance tests * provide blood samples All exercise tests will be on an exercise bike. After 28 (or 46 for pre-menopausal females) days to make sure the supplement has left the body fully, participants will consume the opposite supplement and repeat the tests.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria5

  • Participants will be deemed eligible to participate provided they are willing and able to follow the study instructions and
  • are able to take part in intense exercise (as assessed via Physical Activity Readiness Questionnaire (PARQ))
  • are able to consume a dietary supplement
  • are not overweight/obese (assessed by BMI)
  • do not have any cardiovascular, respiratory, metabolic or musculoskeletal disorders, or any other contraindication to the performance of maximal exercise.

Exclusion Criteria6

  • Aged 31-49 and aged 66+.
  • underlying illness or injury (assessed via PARQ)
  • overweight or obese individuals (BMI of >30 kg.m-2).
  • Cardiovascular, respiratory, metabolic or musculoskeletal disorders (assessed by screening form).
  • Use of dietary supplements, tobacco smoking.
  • Pregnant

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Interventions

DIETARY_SUPPLEMENTMitochondrial Substrate Supplement

Mitochondrial Substrate supplement, 2xdaily 65 mL drink

DIETARY_SUPPLEMENTPlacebo Supplement

Placebo supplement, 2xdaily 65 mL drink


Locations(1)

Richards Building St. Lukes Campus University of Exeter

Exeter, Devon, United Kingdom

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NCT06374641


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