RecruitingNot ApplicableNCT06379243

Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures

Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures: a Multicenter Prospective Cohort Study


Sponsor

The Seventh Affiliated Hospital of Sun Yat-sen University

Enrollment

560 participants

Start Date

Dec 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

In this project, IDEAL-IQ technology and PDFF and R2\* image-based imaging methods are used to analyze the intrinsic relationship between preoperative vertebral bone marrow fat content, magnetic susceptibility properties of bone tissue and bone strength (bone volume and bone mass), to explore the mechanism of vertebral re-fracture after PVP / PKP, and to explore the imaging markers for the risk of postoperative vertebral re-fracture after PVP / PKP. To construct a precise and individualized risk assessment model of vertebral re-fracture after PVP/ PKP by combining clinical risk factors, preoperative quantitative MRI parameters (PDFF, R2\*) and imaging characteristics, so as to achieve the goal of objectively and accurately evaluating the risk of vertebral re-fracture at the early stage of the postoperative period (1 year).


Eligibility

Min Age: 50 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called PVP/PKP for people with compression fracture, osteoporosis fracture, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 50 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPVP/PKP

PVP or PKP surgery in patients with osteoporotic vertebral compression fractures


Locations(1)

The Seventh Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China

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NCT06379243


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