New Biomarkers and Therapeutic Targets in Osteoporosis Via Omics Technologies
Identification of New Biomarkers and Potential Therapeutic Targets in Clinical Osteoporosis Using Omics Technologies
National and Kapodistrian University of Athens
60 participants
Jul 3, 2024
OBSERVATIONAL
Conditions
Summary
This study aims to discover novel biomarkers and therapeutic targets for osteoporosis through the use of advanced omics technologies, including proteomics and metabolomics. By analyzing bone and plasma samples from patients with osteoporosis, the research seeks to understand the underlying mechanisms of the disease and identify potential diagnostic and therapeutic biomarkers.
Eligibility
Inclusion Criteria2
- Postmenopausal Female Patients with osteoporotic subcapital femoral neck fracture (Arm 1)
- Postmenopausal Female Patients with hip osteoarthritis that will undergo Total Hip Replacement (Arm 2)
Exclusion Criteria2
- Patients that have undergone before osteoporotic fractures
- Patients with severe cardiovascular, pulmonary, autoimmune, or urinary system conditions
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Interventions
Intervention: Bone samples will be collected during surgery from the femoral neck (which is typically removed and discarded in these operations) and fasting morning blood samples.
Locations(1)
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NCT06525688