RecruitingNot ApplicableNCT06379646

An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease

An Exploratory Clinical Study of the Safety and Efficacy of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune Disease


Sponsor

China Immunotech (Beijing) Biotechnology Co., Ltd.

Enrollment

6 participants

Start Date

Apr 24, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

An exploratory clinical study of the safety and efficacy of YTS109 cell injection in subjects with recurrent/refractory autoimmune disease


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study tests an experimental cell therapy called YTS109 — a type of engineered immune cell (CAR-T cell) — for patients with autoimmune diseases (like lupus or rheumatoid arthritis) that have not responded to standard treatments. **You may be eligible if...** - You are between 18 and 65 years old - You have a confirmed autoimmune disease that has not responded to standard therapy - Your B cells (immune cells) test positive for a marker called CD19 - Your blood counts, liver, kidney, heart, and clotting functions are within acceptable ranges - You are willing to use contraception if able to have children **You may NOT be eligible if...** - You are outside the 18-65 age range - Your organ functions are too impaired for the treatment - You are pregnant or breastfeeding - You are unwilling or unable to meet the study requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERYTS109

Subjects will receive YTS109 Cell Injection(3E6STAR+T cell/kg) once in this study.


Locations(1)

Shanghai Changzheng Hospital

Shanghai, Shanghai Municipality, China

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NCT06379646


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