Clinical Study of CAR-T Cell Therapy Following ASCT for R/R B-cell Non-Hodgkin's Lymphoma

This study tests whether adding CAR-T cell therapy (engineered immune cells that attack cancer) after an autologous stem cell transplant (a transplant using your own stem cells) improves outcomes in patients with relapsed or treatment-resistant large B-cell non-Hodgkin's lymphoma. **You may be eligible if...** - You are between 18 and 65 years old - You have large B-cell lymphoma that has relapsed or not responded to prior treatment - You have had at least one prior treatment - Your cancer has measurable tumor lesions - Your heart, kidney, and liver function are adequate - Your blood counts meet minimum requirements **You may NOT be eligible if...** - You are outside the 18-65 age range - You have very poor organ function or blood counts - You are pregnant or unwilling to use contraception - You have active uncontrolled infections Talk to your doctor to see if this trial is right for you.