Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following DRF Fixation
The Effect of Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following Distal Radius Fracture Fixation: a Randomized Controlled Trial - The TRADR Study
University Health Network, Toronto
90 participants
Aug 13, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this study is to find out whether the use of topical tranexamic acid (TXA) into the surgical wound will result in less post-operative pain, less pain killer use, and better post-operative use of the wrist in people undergoing surgery for a wrist fracture compared to not using topical TXA (placebo).
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
10mL of 100mg/mL TXA will be administered into the surgical wound prior closure.
10mL of 100mg/mL normal saline will be administered into the surgical wound prior closure.
Locations(1)
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NCT06384456