Skin Cancer Clinical Trials

49 recruiting

Skin Cancer Trials at a Glance

76 actively recruiting trials for skin cancer are listed on ClinicalTrialsFinder across 6 cities in 20 countries. The largest study group is Not Applicable with 22 trials, with the heaviest enrollment activity in Boston, London, and Salt Lake City. Lead sponsors running skin cancer studies include Alpha Tau Medical LTD., University of Utah, and Fundacion Clinic per a la Recerca Biomédica.

Browse skin cancer trials by phase

Treatments under study

About Skin Cancer Clinical Trials

Looking for clinical trials for Skin Cancer? There are currently 49 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Skin Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Skin Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 76 trials

Recruiting
Not Applicable

Pilot Study of Bone Mineral Density Changes During Anti-PD-1 Immunotherapy

Melanoma (Skin Cancer)Renal Cell Carcinoma (Kidney Cancer)Breast Cancer (Triple Negative Breast Cancer (TNBC))
Jessica Mezzanotte Sharpe25 enrolled1 locationNCT07555210
Recruiting
Phase 2Phase 3

A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma

Unresectable MelanomaCutaneous MelanomaMelanoma (Skin Cancer)+1 more
Linnaeus Therapeutics, Inc.135 enrolled9 locationsNCT06624644
Recruiting
Phase 1

Phase Ib Study of AlpeliSib With PEmbroLizumab in Patients With mEtastatic Breast caNcer or melanomA (SELENA)

Breast CancerMelanoma (Skin Cancer)Brain Metastasases
M.D. Anderson Cancer Center50 enrolled1 locationNCT06545682
Recruiting
Not Applicable

Electrochemotherapy (ECT) in Patients With Primary Visceral Tumors and/or Secondary Visceral Localizations, of Any Histotype

Liver CancerMelanomaMerkel Cell Carcinoma+9 more
Istituto Oncologico Veneto IRCCS24 enrolled1 locationNCT06753136
Recruiting
Phase 3

NO Re-excision MelanomA - NORMA 2

Melanoma (Skin Cancer)
Marieke Goodijk1,749 enrolled21 locationsNCT07530887
Recruiting
Phase 1Phase 2

Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC)

Cutaneous Squamous Cell CarcinomaSkin Cancers - Squamous Cell Carcinoma
Falo, Louis, MD48 enrolled1 locationNCT05377905
Recruiting
Not Applicable

Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC

Head and Neck Squamous Cell CarcinomaSkin Cancer
Alpha Tau Medical LTD.48 enrolled3 locationsNCT05047094
Recruiting
Not Applicable

Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals

Skin CancerHeat Tolerance
University of Thessaly80 enrolled2 locationsNCT07510061
Recruiting
Not Applicable

High-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO Trial

Advanced MelanomaSkin CancerMelanoma (Skin)
Fred Hutchinson Cancer Center40 enrolled2 locationsNCT06298734
Recruiting
Not Applicable

Cohort Evaluation of Body Fluids Early Detection of Cancer in High-risk Individuals

Risk of Breast CancerRisk of Gynaecological CancerRisk of Colorectal Cancer+14 more
Gustave Roussy, Cancer Campus, Grand Paris5,909 enrolled1 locationNCT06907095
Recruiting
Not Applicable

Early Detection of Skin Tumors Using a Telemedicine Tool in Primary Care

Skin Cancer Prevention
Institute of Health Information and Statistics of the Czech Republic1,440 enrolled5 locationsNCT07349940
Recruiting
Early Phase 1

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Skin CancerKidney Transplant Recipients
Rhode Island Hospital30 enrolled1 locationNCT05702398
Recruiting
Phase 1Phase 2

Early Phase Study of KESONOTIDE™in Participants With Solid Tumours

Breast CancerLung CancersOvarian Cancer+4 more
Filamon LTD80 enrolled3 locationsNCT06926075
Recruiting
Phase 1Phase 2

Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors

Melanoma (Skin Cancer)HER2-low Hormone Receptor Positive Breast Cancer
Aminex Therapeutics, Inc.92 enrolled8 locationsNCT07287917
Recruiting

A Study of Biological, Genetic, and Constitutional Factors and Non-invasive Monitoring to Assess Personal Cancer Risks

Breast CancerOvarian CancerColo-rectal Cancer+2 more
Fondazione del Piemonte per l'Oncologia850 enrolled1 locationNCT07469709
Recruiting
Phase 2

A Phase II Clinical Trial on Neo-adjuvant Pembrolizumab in Patients With pT3b-T4a/b cN0M0 Melanoma.

Melanoma (Skin Cancer)
Universitair Ziekenhuis Brussel49 enrolled1 locationNCT07448831
Recruiting

Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Breast CancerEsophageal CancerProstate Cancer+10 more
Washington University School of Medicine100 enrolled1 locationNCT04354064
Recruiting
Not Applicable

Immunotherapy Efficacy and PD-L1 as a Predictive Biomarker in Metastatic Melanoma in Slovenia

Metastatic MelanomaSkin Cancer
Institute of Oncology Ljubljana100 enrolled1 locationNCT07422779
Recruiting
Phase 2

TIL Therapy in cSCC and MCC

Merkel Cell CarcinomaCutaneous Squamous Cell CarcinomaSkin Cancer+1 more
Karam Khaddour, MD, MS14 enrolled1 locationNCT07288073
Recruiting
Not Applicable

Hybrid Effectiveness-Implementation Trial to Integrate Precision Skin Cancer Risk Feedback in FQHCs

Skin Cancer
H. Lee Moffitt Cancer Center and Research Institute2,900 enrolled2 locationsNCT07222995