RecruitingNot ApplicableNCT06385834

The Effect of Morning vs Evening Aerobic Exercise Training on Cardiac Remodeling and Function Improvement in Patients After ST Elevation Myocardial Infarction


Sponsor

RenJi Hospital

Enrollment

201 participants

Start Date

Apr 30, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of the study was to intervene in the Aerobic exercise time of patients with STEMI and to explore the optimal exercise time for STEMI patients


Eligibility

Min Age: 17 YearsMax Age: 75 Years

Inclusion Criteria7

  • Between 18 and 75-years-old;
  • Typical symptoms of acute myocardial infarction within 24 hours, with ST segment elevation of ≥1mm in two consecutive leads on electrocardiogram
  • After receiving complete revascularization treatment
  • Cardiac function grading I to II without any other serious complications
  • Left ventricular ejection fraction >30%
  • Compliant with the guidelines of the American College of Cardiology/American Heart Association for participating in cardiac rehabilitation standards
  • Signed written informed consent.

Exclusion Criteria6

  • Patients with unstable angina
  • severe symptomatic congestive heart failure detectable myocardial ischemia
  • valvular disease requiring surgery
  • severe ventricular arrhythmias
  • severe concomitant life-threatening diseases such as cancer, and rheumatoid disease
  • osteoarticular diseases that may affect the exercise process

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Interventions

OTHERMorning aerobic exercise

Patients were randomly assigned to morning aerobic exercise training for a 12-week outpatient training program that included a combination of warm-up, aerobic, and relaxation exercises three times a week. Each class consists of 10 minutes of warm-up training, 40 minutes of aerobic training and 10 minutes of relaxation training. The intensity of aerobic exercise training will be personalized. According to the guidance of relevant guidelines, the exercise intensity of patients will be determined according to the results of their first cardiopulmonary exercise experiment, and the exercise load will be gradually increased according to the exercise program until the predetermined goal is reached. Patient fatigue levels will be monitored throughout the exercise using the borg scale.

OTHEREvening aerobic exercise

Patients were randomly assigned to evening aerobic exercise training for a 12-week outpatient training program that included a combination of warm-up, aerobic, and relaxation exercises three times a week. Each class consists of 10 minutes of warm-up training, 40 minutes of aerobic training and 10 minutes of relaxation training. The intensity of aerobic exercise training will be personalized. According to the guidance of relevant guidelines, the exercise intensity of patients will be determined according to the results of their first cardiopulmonary exercise experiment, and the exercise load will be gradually increased according to the exercise program until the predetermined goal is reached. Patient fatigue levels will be monitored throughout the exercise using the borg scale.


Locations(1)

Renji Hospital

Shanghai, China

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NCT06385834


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