RecruitingPhase 2NCT06386003

Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD

Psilocybin-Assisted Massed Cognitive Processing Therapy for Chronic Posttraumatic Stress Disorder: An Open-label Trial

Sponsor

Unity Health Toronto

Enrollment

15 participants

Start Date

Jun 1, 2026

Study Type

INTERVENTIONAL

Conditions

Post Traumatic Stress Disorder PTSD Chronic PTSD

Summary

This is an open-label trial evaluating feasibility, tolerability, safety and efficacy of psilocybin assisted cognitive processing therapy for chronic Posttraumatic Stress Disorder (PTSD).

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Psilocybin for people with chronic ptsd, ptsd, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPsilocybin

Participants will receive a single dose of psilocybin 25mg combined with 12 sessions of massed CPT, and 2 psychotherapy sessions related to psilocybin over 7 days.

Locations(1)

St. Michael's Hospital, Unity Health Toronto

Toronto, Ontario, Canada

View Full Details on ClinicalTrials.gov

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NCT06386003

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