Reduced Dose Radiotherapy for the Treatment of Indolent Non-Hodgkin Lymphoma

This study tests whether a lower dose of radiation therapy works just as well as the standard dose for treating indolent (slow-growing) non-Hodgkin lymphoma, a type of blood cancer. A lower dose could mean fewer side effects while still effectively shrinking tumors. **You may be eligible if...** - You are 18 or older - You have been diagnosed with follicular lymphoma (grades 1, 2, or 3A), marginal zone lymphoma, or follicle center lymphoma - Your cancer can be at any stage — newly diagnosed, relapsed, or not responding to prior treatment - You are well enough to function reasonably well day-to-day (ECOG score 3 or less) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have T-cell lymphoma - You are being treated for small/chronic lymphocytic lymphoma - You have grade 3B follicular lymphoma Talk to your doctor to see if this trial is right for you.