RecruitingNCT06394089

Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: Study Protocol

Effect of Degenerative Spondylolisthesis on the Clinical Outcome of Unilateral Biportal Endoscopy for Lumbar Spinal Stenosis: a Single-center, Prospective Cohort Trial Protocol

Sponsor

Beijing Friendship Hospital

Enrollment

150 participants

Start Date

Mar 1, 2024

Study Type

OBSERVATIONAL

Conditions

Lumbar Spinal Stenosis Degenerative Spondylolisthesis

Summary

A single-center, prospective cohort trial aims to provide stronger evidence regarding the impact of degenerative spondylolisthesis on the clinical outcome of unilateral biportal endoscopy for lumbar spinal stenosis

Eligibility

Min Age: 50 YearsMax Age: 80 Years

Inclusion Criteria5

Age range: 50-80 years
Diagnosis of LSS affecting 1-2 vertebral levels
Predominant manifestation of neurogenic intermittent claudication, with ineffective conservative treatment for at least 3 months
Presence of lumbar DS of less than grade II and absence of spine instability
Willingness to participate in the study and complete follow-up assessments.

Exclusion Criteria7

Diagnosis of isthmic lumbar spondylolisthesis or lumbar DS of grade ≥II
Evidence of instability at the affected vertebral level (intervertebral angle change > 15° and/or vertebral translation ≥ 4.5 mm in standing flexion-extension radiographs of the lumbar spine)
History of prior surgery at the affected vertebral level
Presence of scoliosis with a Cobb angle >20º
Presence of other conditions affecting the lumbar spine (infection, tumor, fracture, neurological diseases, and others)
Medical disorders that preclude surgical tolerance
Participation in other clinical research projects related to the treatment of lumbar spinal stenosis.