RecruitingNCT06396143

Research on Intelligent Screening and Decision-making for Neoadjuvant Therapy in Locally Advanced Gastric Cancer Based on Multi-omics Integration


Sponsor

Zhejiang University

Enrollment

120 participants

Start Date

Jul 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

In this study, investigators utilize a radiopathomics integrated Artificial Intelligence (AI) supportive system to predict tumor response to neoadjuvant chemoradiotherapy (nCRT) before its administration for patients with locally advanced gastric cancer (LAGC). By the system, the postoperative tumor regression grade (TRG) of the participants will be identified based on the radiopathomics features extracted from the pre-nCRT Enhanced CT and biopsy images. The ability to predict TRG will be validated in this multicenter, prospective clinical study.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study develops and validates an intelligent computer system that helps doctors decide which breast cancer patients would benefit from neoadjuvant therapy — chemotherapy given before surgery to shrink the tumor — using imaging and clinical data. **You may be eligible if...** - You have been newly diagnosed with breast cancer and are being considered for treatment before surgery - You are an adult woman at least 18 years old - You are willing to have your imaging and clinical data used for this research **You may NOT be eligible if...** - You have already undergone surgery for this breast cancer - You have metastatic (stage IV) breast cancer - You decline to have your data included in the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.


Locations(4)

Gastrointestinal Department of First Affiliated Hospital of Zhejiang University

Hanzhou, Zhejiang, China

Gastrointestinal Department of Second Affiliated Hospital of Zhejiang University

Hanzhou, Zhejiang, China

Gastrointestinal Department of Zhejiang Cancer Hospital

Hanzhou, Zhejiang, China

Shaoxing Shangyu People's Hospital

Shaoxing, Zhejiang, China

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06396143


Related Trials