RecruitingPhase 2NCT06399263

Study of Psilocybin for Anorexia in Young Adults


Sponsor

Marissa Raymond-Flesch, MD, MPH

Enrollment

40 participants

Start Date

Nov 18, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a single site trial of psilocybin therapy for the treatment of refractory Anorexia Nervosa in young adults. The psilocybin therapy will include three preparatory sessions, psilocybin dosing session one (20mg), two integration sessions, psilocybin dosing session two (up to 25mg), and three final integration sessions. Eating disorder symptoms will be measured pre and post treatment. One to two family member(s) of each young adult participant will be enrolled in the study. One of which will be required to attend a portion of two preparatory sessions and a portion of two integration sessions and receive psychoeducation about supporting the young adult participant through preparation and integration for psilocybin therapy. Investigators hypothesize that psilocybin will increase cognitive flexibility and that this increase will predict long-term changes in cognitive rigidity, habitual eating, and exercise behaviors in patients with Anorexia Nervosa.


Eligibility

Min Age: 18 YearsMax Age: 25 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a behavioral approach called Preparation and Integration Sessions and a drug called Psilocybin for people with anorexia nervosa. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 25 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPsilocybin

The psilocybin will include two dose administration sessions, first a 20mg administration, and second an administration of up to 25mg.

BEHAVIORALPreparation and Integration Sessions

The psilocybin therapy will include three preparatory sessions, two dose A integration sessions, and four final integration sessions.


Locations(2)

University of California, San Francisco

San Francisco, California, United States

University of California, San Francisco

San Francisco, California, United States

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NCT06399263


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