RecruitingPhase 3NCT06399705

REvascularization CHoices Among Under-Represented Groups Evaluation: The RECHARGE Trial - Minorities

Sponsor

Weill Medical College of Cornell University

Enrollment

600 participants

Start Date

Oct 2, 2024

Study Type

INTERVENTIONAL

Conditions

Coronary Artery Disease

Summary

This is a research study in minorities to compare the outcomes of two procedures that restore blood flow to the arteries of the heart. In one procedure the blockages are ballooned and then stented with a small wire mesh tube through a small incision in the wrist or the groin. The other procedure is an open-heart operation in which healthy blood vessels from inside the chest, leg, and/or forearm are used to "bypass" the blockages (like a detour). Outcomes will be measured by comparing survival and improvement in quality-of-life.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two heart procedures for minority patients with significant coronary artery disease: bypass surgery (CABG) versus stenting (PCI). The goal is to understand which approach leads to better outcomes and quality of life specifically in underrepresented populations. **You may be eligible if...** - You identify as a racial or ethnic minority - You are 18 or older - You have multi-vessel or left main coronary artery disease - Your heart team has determined that either bypass surgery or stenting could be an appropriate option for you **You may NOT be eligible if...** - You had a heart attack (STEMI) in the last 3 days - You are in cardiogenic shock (when the heart can't pump enough blood) - You have had stenting in the last year or any prior bypass surgery - You are pregnant or planning to become pregnant within one year - You have a life expectancy of less than 3 years due to another illness Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURECoronary artery bypass grafting

Coronary artery bypass grafting (CABG), also called heart bypass surgery, is a medical procedure to improve blood flow to the heart.

PROCEDUREPercutaneous coronary intervention

Percutaneous coronary intervention (PCI) is a non-surgical procedure used to treat the blockages in a coronary artery; it opens up narrowed or blocked sections of the artery, restoring blood flow to the heart

Locations(18)

Adventist Health Glendale

Glendale, California, United States

Emory University

Atlanta, Georgia, United States

Ascension St. Vincent Cardiovascular Research Institute

Carmel, Indiana, United States

Baptist Health Lexington

Lexington, Kentucky, United States

Baptist Health Louisville

Louisville, Kentucky, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

Englewood Hospital

Englewood, New Jersey, United States

NewYork-Presbyterian Hospital - Queens

Flushing, New York, United States

Icahn School of Medicine - Mount Sinai Morningside

New York, New York, United States

Icahn School of Medicine - Mount Sinai Hospital

New York, New York, United States

Columbia University Irving Medical Center/NewYork-Presbyterian Hospital

New York, New York, United States

Weill Cornell Medicine/NewYork-Presbyterian Hospital

New York, New York, United States

Westchester Medical Center

Valhalla, New York, United States

Duke University

Durham, North Carolina, United States

Ohio State University

Columbus, Ohio, United States

Methodist Le Bonheur Healthcare

Memphis, Tennessee, United States

Ascension Saint Thomas Hospital

Nashville, Tennessee, United States

Baylor Scott and White

Dallas, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT06399705

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