RecruitingNot ApplicableNCT06400290

Multivessel Balloon Occlusion to Investigate Obstructive Coronary Artery Disease and aNgina

Sponsor

Imperial College London

Enrollment

60 participants

Start Date

Jun 13, 2024

Study Type

INTERVENTIONAL

Conditions

Stable Angina Multivessel Coronary Artery Disease

Summary

ORBITA-MOON is a double-blinded, placebo-controlled experimental study that aims to understand how the different coronary artery stenoses contribute to overall clinical angina in patients with multi-vessel coronary artery disease. This study will investigate the symptoms conferred by each stenosis, induced by experimental ischaemia, for 60 patients with multi-vessel coronary artery disease.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Percutaneous coronary intervention (PCI) and Symptom assessment during experimentally induced ischaemia for people with multivessel coronary artery disease and stable angina. The study is currently recruiting participants at 9 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPercutaneous coronary intervention (PCI)

Coronary artery stenting for stable angina

DIAGNOSTIC_TESTSymptom assessment during experimentally induced ischaemia

Transient experimental balloon occlusion across coronary stenosis to determine the symptoms conferred by ischaemia at this stenosis.

Locations(9)

Essex Cardiothoracic Centre

Basildon, United Kingdom

Royal Bournemouth Hospital

Bournemouth, United Kingdom

Royal Sussex County Hospital

Brighton, United Kingdom

Imperial College NHS Trust

London, United Kingdom

Royal Free London NHS Foundation Trust

London, United Kingdom

St Georges University Hospital

London, United Kingdom

Nottingham City Hospital

Nottingham, United Kingdom

Portsmouth Hospitals University NHS Trust

Portsmouth, United Kingdom

University Hospital Southampton

Southampton, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT06400290

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