RecruitingNCT06405321

Conversion or Neoadjuvant Therapy in Hepatocellular Carcinoma

Conversion or Neoadjuvant Therapy in Hepatocellular Carcinoma: A Multicenter Retrospective Study in Guangxi, China (GUIDANCE)


Sponsor

Guangxi Medical University

Enrollment

2,000 participants

Start Date

Jan 1, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

This multicenter retrospective study which included patients with hepatocellular carcinoma (HCC) who received conversion or neoadjuvant therapy to explore the best treatment options and the best benefit group.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This observational study collects and analyses data from patients with hepatocellular carcinoma (HCC, the most common type of primary liver cancer) who received "conversion" or "neoadjuvant" therapy — treatment given before surgery to shrink the tumor enough to make curative surgery possible. **You may be eligible if...** - You have a confirmed diagnosis of liver cancer (HCC), either by biopsy or clinical criteria - You received pre-surgical treatment such as HAIC (chemo infused into liver arteries), TACE (targeted chemo embolization), targeted therapy (TKIs), immunotherapy, or radiation therapy as your initial treatment - Your general health score (ECOG) is 0 or 1 - Your liver function score (Child-Pugh) is between 5 and 7 - You have at least 3 months of follow-up data available **You may NOT be eligible if...** - You have had another active cancer in the past 5 years - Your medical records are incomplete - Your follow-up time is less than 3 months Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGConversion or neoadjuvant therapy.

Patients with hepatocellular carcinoma received conversion or neoadjuvant therapy.


Locations(1)

Jian-Hong Zhong

Nanning, China, China

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NCT06405321


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