RecruitingNCT06405412

Effects of Malnutrition on Respiratory and Renal Functions in Patients Undergoing Peroral Endoscopic Myotomy (POEM)

Sponsor

Umraniye Education and Research Hospital

Enrollment

60 participants

Start Date

Nov 1, 2023

Study Type

OBSERVATIONAL

Conditions

Esophageal Achalasia

Summary

The hypothesis of this study is to investigate cardiorespiratory and renal complications in patients under general anesthesia undergoing POEM surgery.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

Criteria for inclusion in the study:
Patients diagnosed with achalasia and suitable for POEM treatment by gastroenterology physicians
ASA 1-3
Between the ages of 18-80

Exclusion Criteria11

Criteria for exclusion from the study:
Those with a known history of active lung infection, advanced COPD, or respiratory failure
Patients with EF below 40%, severe ischemic heart failure, presence of valve disease
Those with bleeding diathesis and severe thrombocytopenia (limit 30-50 thousand)
severe kidney dysfunction
In the presence of known intolerance or allergy to certain medications for sedation, analgesia, or both
Pre-existing increased intracranial pressure
Having a BMI >30
Severe uncorrected hypovolemiaHistory of radiotherapy to the esophagus
History of mucosal resection or ablation in the area where POEM will be applied
Presence of cirrhosis and portal hypertension.