RecruitingNCT06408142

Universal Test and Connect for HIV Service Delivery in South Africa

Universal Test and Connect for HIV Service Delivery in South Africa and Baltimore

Sponsor

Johns Hopkins University

Enrollment

2,000 participants

Start Date

Jan 19, 2026

Study Type

OBSERVATIONAL

Conditions

Human Immunodeficiency Virus

Summary

The goal of this study is to determine how many patients with HIV or at high risk of getting HIV attend the Emergency Department (ED) in South Africa (SA). The investigators will integrate HIV assessment in the ED and see how many people who would be a candidate for a drug that prevents HIV (PrEP). Universal test and connect (UTC) is a strategy that universally tests all patients and connects patients to long-term care, whether HIV positive or negative, including referrals for PrEP. The investigator's goal is to use UTC across two busy 24-hr EDs in Cape Town, SA.

Eligibility

Min Age: 12 Years

Plain Language Summary

Simplified for easier understanding

This study aims to improve HIV testing and connecting people to care or prevention in emergency departments in South Africa. It tests a universal testing program where everyone who comes to the emergency room is offered an HIV test, and those who test negative can be connected to HIV prevention (PrEP). **You may be eligible if...** - You are visiting an emergency department in South Africa - You are 12 years or older - For the PrEP prevention part: you do not have HIV, have no kidney disease, and are not already taking PrEP **You may NOT be eligible if...** - You are unable to consent (e.g., unconscious, critically ill) - You already have HIV and are in the testing phase of the study - You have a contraindication to PrEP (for the prevention component) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTHIV testing

Point of Care HIV testing universally regardless of risk factors

OTHERIn-depth interview

In-depth interviews of providers using Normalization Process Theory semi-structured interview guide to assess provider perspectives of PrEP delivery in the ED

Locations(1)

Gugulethu Community Health Centre

Cape Town, Western Cape, South Africa

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