Universal Test and Connect for HIV Service Delivery in South Africa
Universal Test and Connect for HIV Service Delivery in South Africa and Baltimore
Johns Hopkins University
2,000 participants
Jan 19, 2026
OBSERVATIONAL
Conditions
Summary
The goal of this study is to determine how many patients with HIV or at high risk of getting HIV attend the Emergency Department (ED) in South Africa (SA). The investigators will integrate HIV assessment in the ED and see how many people who would be a candidate for a drug that prevents HIV (PrEP). Universal test and connect (UTC) is a strategy that universally tests all patients and connects patients to long-term care, whether HIV positive or negative, including referrals for PrEP. The investigator's goal is to use UTC across two busy 24-hr EDs in Cape Town, SA.
Eligibility
Inclusion Criteria4
- Patients attending the Emergency Department
- Ages \> or = 12 years old in South Africa
- Nurses, physicians, or advanced practice providers (APPs) who work regularly in the Emergency Department at one of the clinical sites.
- Consent to a recorded in-depth interview and/or Normalizing Process Theory (NPT) survey
Exclusion Criteria5
- Patients unable to provide written informed consent - i.e., have a depressed level of consciousness (head trauma or concurrent alcohol/substance abuse), determined as critically ill (triage score of "emergent"), or
- do not speak a language spoken by the study team (English, Afrikaans, and Xhosa).
- In-depth interviews and surveys to providers:
- Providers who have already been interviewed (if working at both clinical sites)
- Providers who do not consent to an interview or a survey.
Interventions
Point of Care HIV testing universally regardless of risk factors
In-depth interviews of providers using Normalization Process Theory semi-structured interview guide to assess provider perspectives of PrEP delivery in the ED
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06408142