Emergency Department Clinical Trials

23 recruitingLast updated: May 11, 2026

There are 23 actively recruiting emergency department clinical trials across 10 countries. Studies span Not Applicable, Phase 4. Top locations include Danville, Pennsylvania, United States, Cape Town, Western Cape, South Africa, Chicago, Illinois, United States. Updated daily from ClinicalTrials.gov.


Emergency Department Trials at a Glance

23 actively recruiting trials for emergency department are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 9 trials, with the heaviest enrollment activity in Danville, Cape Town, and Chicago. Lead sponsors running emergency department studies include Geisinger Clinic, Associate Professor Timothy Kenealy, and Ann & Robert H Lurie Children's Hospital of Chicago.

Browse emergency department trials by phase

Treatments under study

About Emergency Department Clinical Trials

Looking for clinical trials for Emergency Department? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Emergency Department trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Emergency Department clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 23 trials

Recruiting

PREMEDICAL is a Clinical Investigation Aiming to Create a Data Basis That Can be Used to Enrich Information Collected in the Course of the Classic Patient Journey. Patients in the Emergency Department Will be Asked to Answer Patient-related and Symptom-oriented Questions. Minimum Age is 18 Years

Emergency department triage
XUND Solutions GmbH3,000 enrolled1 locationNCT06933550
Recruiting
Not Applicable

An Emergency Department (ED) Provider Centered Intervention for Non-Traumatic Dental Condition Management (NTDC)

Emergency Department VisitOdontalgia
University of Florida60 enrolled1 locationNCT06330207
Recruiting
Not Applicable

Supporting Caregivers Following Mental Health Emergency Department Visits

Caregiver ParticipationSafety PlanEmergency department presentation
Ann & Robert H Lurie Children's Hospital of Chicago75 enrolled1 locationNCT07411300
Recruiting
Not Applicable

CMSL Ambulatory Sensitive Condition Nudge Study 2

Emergency Department VisitsBehavioral InterventionNurse Care Coordination
Geisinger Clinic12,990 enrolled1 locationNCT07028398
Recruiting
Not Applicable

Modifying the Geriatric Acute & Post-acute Care Coordination Program for Fall Prevention in the Emergency Department for Telehealth

Older Adults (65 Years and Older)Fall PreventionEmergency Department+1 more
University of Colorado, Denver40 enrolled1 locationNCT07034287
Recruiting

Universal Test and Connect for HIV Service Delivery in South Africa

Human Immunodeficiency VirusPre-exposure ProphylaxisEmergency Department+1 more
Johns Hopkins University2,000 enrolled1 locationNCT06408142
Recruiting
Not Applicable

Single Lumen Midline Catheter vs Long Peripheral Intravenous Cather for Difficult Intravenous Access in the ED

Difficult intravenous accessEmergency Department PatientMidline Catheter+1 more
Albany Medical College270 enrolled1 locationNCT06668766
Recruiting
Not Applicable

Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers

Pulmonary Embolism (Diagnosis)Diagnostic ImagingImplementation Science+7 more
Duke University75 enrolled1 locationNCT07159269
Recruiting

Predictors of Emergency Department Use in Frail Patients

ElderlyFrailtyAlzheimer s Disease+3 more
University of Pisa110 enrolled1 locationNCT07259499
Recruiting

The Association Between Post-resuscitation Time Series Management in the Emergency Department and Short-term Outcomes for Out-of-hospital Cardiac Arrest Patients

ResuscitationEmergency DepartmentOutcome
National Taiwan University Hospital6,000 enrolled1 locationNCT06165081
Recruiting
Not Applicable

Impact of Point-of-care Lactate Testing as Triage Supplement on Patient Management Using Manchester Triage System

Emergency Department overcrowdingEmergency department triageEmergency Medicine+1 more
University Medical Centre Maribor200 enrolled1 locationNCT07123857
Recruiting
Not Applicable

Integrated Telemedicine Program Evaluation

TelemedicineEmergency Department VisitsBehavioral Intervention
Geisinger Clinic3,200 enrolled1 locationNCT07042477
Recruiting

Automatic Detection of Eligible Patients to RAUC Protocol (RAUCISABLE)

Emergency Department Visit
Centre Hospitalier Universitaire, Amiens300,000 enrolled1 locationNCT07037719
Recruiting
Not Applicable

The Safe Fast Track Study

Emergency DepartmentNon-specific Complaints
Odense University Hospital1,538 enrolled2 locationsNCT06219486
Recruiting

Droperidol and QTc Interval Changes in ED Patients

Emergency Department PatientQTc Intervals Changes
CHRISTUS Health500 enrolled1 locationNCT06726811
Recruiting

Just Say No to the Just in Case Cannula: An Implementation Science Trial

Unnecessary cannulation in emergency departments (ED)
Monash University108,000 enrolled1 locationACTRN12623001248651
Recruiting

A multicentre, qualitative evaluation of the impact of advertised Emergency Department (ED) wait time on ED patients, potential patients and other stakeholders.

Published Emergency Department wait timesPrivate Emergency MedicineEmergency Medicine
Dr Michael Ben-Meir50 enrolled4 locationsACTRN12619000665134
Recruiting

Very High Intensity Users of Middlemore Hospital Emergency Department

frequent attendance at a hospital emergency departmentlong term conditions
Associate Professor Timothy Kenealy200 enrolled1 locationACTRN12611000496910
Recruiting

Effect of Nurse-run Walk-in Clinic on Emergency Department workload

Emergency Department presentations
The Canberra Hospital60,000 enrolled1 locationACTRN12610000402044
Recruiting

Ultrasound-guided femoral nerve block as a mode of analgesia in patients presenting with a hip fracture to the Emergency Department.

Pain management in patients who have a radiological diagnosis of fractured neck of femur who present to the emergency department.
St Vincents46 enrolled1 locationACTRN12609000526279