RecruitingNot ApplicableNCT06410157

Cardiac-Control Affecting Learning Through Mindfulness (CALM)


Sponsor

University of Southern California

Enrollment

240 participants

Start Date

Jan 14, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Some types of meditation lead heart rate to become more steady as breathing quiets whereas others lead to large heart rate swings up and down (oscillations) as breathing becomes deeper and slower. The current study is designed to investigate how daily mindfulness practice with heart rate biofeedback during breathing in a pattern that either increases or decreases heart rate oscillation affect attention and memory and blood biomarkers associated with Alzheimer's disease.


Eligibility

Min Age: 50 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

The CALM study examines whether a 10-week online mindfulness program can improve learning, memory, and heart health in Black and White adults aged 50 to 70. Researchers are exploring whether reducing stress through mindfulness has measurable effects on the brain and body — and whether results differ by race. **You may be eligible if...** - You are 50 to 70 years old - You identify as Black/African-American or White/European-American - You are post-menopausal (not menstruating for at least one year) or male - You have normal or corrected vision and hearing - You have reliable wifi, an email account, and a phone that receives texts - You can commit up to 50 minutes daily for 10 weeks and attend two in-person visits **You may NOT be eligible if...** - You have a condition that would interfere with cognitive testing or mindfulness exercises - You are currently pregnant or still menstruating - You are not fluent in English Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALDaily practice

Participants will be asked to undergo daily mindfulness practice while regulating (either increase or decrease) heart rate oscillation.


Locations(1)

University of Southern California

Los Angeles, California, United States

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NCT06410157


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