RecruitingPhase 3NCT06413433

Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol

A Phase 3, Randomized, Double-blind, Placebo-Controlled Trial of Solriamfetol in Adults With Binge Eating Disorder (BED)

Sponsor

Axsome Therapeutics, Inc.

Enrollment

450 participants

Start Date

Apr 26, 2024

Study Type

INTERVENTIONAL

Conditions

Binge-Eating Disorder

Summary

ENGAGE (Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol) is a Phase 3, randomized, double-blind, placebo-controlled, multicenter trial to assess the efficacy and safety of solriamfetol for the treatment of binge eating disorder (BED) in adults.

Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo, a drug called Solriamfetol 150 mg, and others for people with binge-eating disorder. The study is currently recruiting participants at 45 locations. People eligible for this study include aged 18 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSolriamfetol 150 mg

Solriamfetol tablets, taken once daily

DRUGSolriamfetol 300 mg

Solriamfetol tablets, taken once daily

DRUGPlacebo

Placebo tablets, taken once daily

Locations(45)

Clinical Research Site

Encino, California, United States

Clinical Research Site

Garden Grove, California, United States

Clinical Research Site

Long Beach, California, United States

Clinical Research Site

Mission Viejo, California, United States

Clinical Research Site

San Diego, California, United States

Clinical Research Site

Santa Ana, California, United States

Clinical Research Site

Walnut Creek, California, United States

Clinical Research Site

West Covina, California, United States

Clinical Research Site

Colorado Springs, Colorado, United States

Clinical Research Site

Cromwell, Connecticut, United States

Clinical Research Site

Clermont, Florida, United States

Clinical Research Site

Fort Myers, Florida, United States

Clinical Research Site

Jacksonville, Florida, United States

Clinical Research Site

Lauderhill, Florida, United States

Clinical Research Site

Miami, Florida, United States

Clinical Research Site

Miami, Florida, United States

Clinical Research Site

Miami Lakes, Florida, United States

Clinical Research Site

Miami Lakes, Florida, United States

Clinical Research Site

Orlando, Florida, United States

Clinical Research Site

Orlando, Florida, United States

Clinical Research Site

Marietta, Georgia, United States

Clinical Research Site

Overland Park, Kansas, United States

Clinical Research Site

Boston, Massachusetts, United States

Clinical Research Site

Methuen, Massachusetts, United States

Clinical Research Site

Saint Charles, Missouri, United States

Clinical Research Site

Cherry Hill, New Jersey, United States

Clinical Research Site

Princeton, New Jersey, United States

Clinical Research Site

Mount Kisco, New York, United States

Clinical Research Site

New York, New York, United States

Clinical Research Site

Raleigh, North Carolina, United States

Clinical Research Site

Cincinnati, Ohio, United States

Clinical Research Site

Mason, Ohio, United States

Clinical Research Site

Middleburg Heights, Ohio, United States

Clinical Research Site

North Canton, Ohio, United States

Clinical Research Site

Portland, Oregon, United States

Clinical Research Site

Allentown, Pennsylvania, United States

Clinical Research Site

Media, Pennsylvania, United States

Clinical Research Site

Greenville, South Carolina, United States

Clinical Research Site

North Charleston, South Carolina, United States

Clinical Research Site

Memphis, Tennessee, United States

Clinical Research Site

Austin, Texas, United States

Clinical Research Site

Austin, Texas, United States

Clinical Research Site

Dallas, Texas, United States

Clinical Research Site

San Antonio, Texas, United States

Clinical Research Site

Draper, Utah, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT06413433

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