RecruitingNCT06413459

Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis


Sponsor

Ospedale San Raffaele

Enrollment

40 participants

Start Date

Apr 8, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

In this project the investigators aim to identify new biological markers by characterizing the response/inflammation associated with the development and progression of M. abscessus lung disease in patients suffering from cystic fibrosis with the aim of increasing current knowledge available on the development and progression of lung disease.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Patients with a certain diagnosis of cystic fibrosis and visited during normal clinical practice, in accordance with the standard operating procedures in force at the Centres.
  • Both sexes
  • Age \>18 years
  • Obtaining informed consent for patients (based on the procedures established by the protocol).

Exclusion Criteria1

  • Patients unable to understand the instructions and information provided and be able to adequately accept the study methods.

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Interventions

OTHERLuminex; scRNAsec

Evaluation of specific cell populations associated with development of M. abscessus lung disease; evaluation of circulating factors related to immunoresponses


Locations(1)

Ospedale San Raffaele

Milan, MI, Italy

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NCT06413459


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