LEARNER- Low dosE AspiRiN prEterm tRial (Angola)

This study is testing whether low-dose aspirin can reduce the risk of preterm birth (being born too early) in pregnant women in Angola who have sickle cell disease — an inherited blood disorder that can cause serious pregnancy complications. **You may be eligible if...** - You are pregnant and 15 years old or older - You have sickle cell disease - You are attending specific hospitals or health facilities in Luanda, Angola - You are willing to attend regular appointments and consent to participate - You are in your first or second trimester (before 28 weeks of pregnancy) **You may NOT be eligible if...** - You are in your third trimester (after week 27 of pregnancy) - You have HIV infection - You have diabetes - You have chronic high blood pressure - You have significant liver disease - You have sickle cell-related kidney disease - You are carrying more than one baby - You have a known allergy to aspirin - You received a blood transfusion in the past 3 months Talk to your doctor to see if this trial is right for you.