RecruitingPhase 2NCT06419205

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

A Phase 2 Study to Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Clinical Activity of ADX-097 Administered Subcutaneously in Male and Female Participants Aged 16 Years or Older With Immunoglobulin A Nephropathy (IgAN), Lupus Nephritis (LN), or Complement Component 3 Glomerulopathy (C3G)


Sponsor

Akebia Therapeutics

Enrollment

30 participants

Start Date

Jul 30, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

A Phase 2 Study to Evaluate the Safety, Pharmacodynamics, Pharmacokinetics, and Clinical Activity of ADX-097 Administered Subcutaneously in Male and Female Participants Aged 16 Years or Older with Immunoglobulin A Nephropathy (IgAN), Lupus Nephritis (LN), or Complement Component 3 Glomerulopathy (C3G)


Eligibility

Min Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called ADX-097 for people with c3 (complement component 3) glomerulopathy, iga nephropathy, and other related conditions. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 16 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGADX-097

Subcutaneous Infusions


Locations(2)

Investigator Site #1

Lawrenceville, Georgia, United States

Investigator Site #2

São Paulo, Brazil

View Full Details on ClinicalTrials.gov

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NCT06419205


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