RecruitingNCT03001947

IgA Nephropathy Registration Initiative of High Quality (INSIGHT)


Sponsor

Sun Yat-sen University

Enrollment

10,000 participants

Start Date

Nov 1, 2012

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators are registering all biopsy-proven primary IgA nephropathy (IgAN) patients at recruited hospitals and developing a IgAN database in China. Patients will be follow-up every one year, and both baseline and follow-up information will be entered into the registration system. All-cause and cardiovascular mortality and a composite renal outcome of doubling of serum creatinine and end stage renal failure (ESRD, defined as initiation of dialysis or kidney transplantation) of IgAN patients will be compared using the IgAN database.


Eligibility

Min Age: 14 Years

Inclusion Criteria3

  • Biopsy-proven primary IgAN patients;
  • age ≥14 years old
  • Adequate biopsy sample containing ≥8 glomeruli.

Exclusion Criteria1

  • Secondary causes of mesangial IgA deposition, such as Henoch-Schonlein purpura nephritis, systemic lupus erythematosus, liver cirrhosis and et al; eGFR≤15ml/min/1.73m2 at biopsy.

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Interventions

OTHERNo intervention

Registration of all IgAN patients in the First Affiliated Hospital of Sun Yat-sen University and other hospitals which have signed the contract in China.


Locations(1)

The First Affiliated Hospital, Sun Yat-Sen University

Guangzhou, Guangdong, China

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NCT03001947


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