RecruitingNot ApplicableNCT06425406

Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial

Sponsor

Henan Provincial People's Hospital

Enrollment

48 participants

Start Date

Jun 15, 2024

Study Type

INTERVENTIONAL

Conditions

High-flow Nasal Cannula Children Pre-oxygenation

Summary

Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears. At this critical stage, the residual oxygen of the lung is consumed, resulting in hypoxemia and atelectasis. Therefore, it is necessary to explore the best oxygenation strategy during intubation. In addition, ultrasound has become a common equipment in the operating room. It has the advantages of portability, repeatability, and no radiation, and can provide strong support for the diagnosis of gastric distension.

Eligibility

Min Age: 2 YearsMax Age: 10 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether using high-flow nasal oxygen (HFNC) before and during general anesthesia induction in children undergoing surgery can reduce the risk of low blood oxygen (hypoxemia) that can occur during the brief period when the child stops breathing before a breathing tube is placed. Children are more vulnerable to low oxygen during this window than adults due to their smaller lung reserve. You may be eligible if you are a child aged 2 to 10 with a healthy heart and lungs (ASA class I or II) scheduled for surgery requiring intubation, without any upper airway obstruction, nasal injuries, or recent respiratory infections. Participation involves using the HFNC device during the start of anesthesia, with monitoring by the anesthesia team throughout the procedure. This summary was prepared using AI to help patients understand this research.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEhigh-flow nasal cannula

In group H, mask ventilation was performed after the patient lost spontaneous breathing until the end-expiratory oxygen concentration reached 90 %. The lower mask was taken and HFNC was used to record the patient 's safe apnea time.

Locations(1)

Department of Anaesthesiology and Perioperative Medicine, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital

Zhengzhou, Henan, China

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NCT06425406

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