RecruitingPhase 2NCT06426160

Tocilizumab for Painful Chronic Pancreatitis

Tocilizumab for Painful Chronic Pancreatitis: A Randomised, Placebo-Controlled, Double-blinded, Investigator Initiated Trial (TOPAC Trial)

Sponsor

Soren Schou Olesen

Enrollment

36 participants

Start Date

May 21, 2024

Study Type

INTERVENTIONAL

Conditions

Pancreatitis, Chronic

Summary

This placebo-controlled study will investigate the effect of tocilizumab (an anti-interleukin-6 receptor antibody) on symptom burden, physical functioning, and quality of life in patients with chronic pancreatitis.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Sodium Chloride 0.9% Inj and a drug called Tocilizumab 20 MG/ML [Actemra] for people with pancreatitis, chronic. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTocilizumab 20 MG/ML [Actemra]

Tocilizumab 8 mg/kg every four weeks for 24 weeks.

DRUGSodium Chloride 0.9% Inj

Placebo (Sodium chloride) every four weeks for 24 weeks.

Locations(1)

Centre for Pancreatic Diseases and Mech-Sense research laboratory, Aalborg University Hospital

Aalborg, North Denmark, Denmark

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NCT06426160

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