Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas
Vanderbilt University Medical Center
96 participants
Jun 21, 2024
INTERVENTIONAL
Conditions
Summary
Infections of the pleural space are common, and patients require antibiotics and chest drain placement to evacuate the chest from the infected fluid. Chest drains can get blocked by the drainage fluid and material. For this reason, it is thought that flushing the chest drain with saline solution, can help maintain the patency of the tube. This proposed study will evaluate the impact of regular chest drain flushing on the length of time to chest tube removal and total hospitalization as well as improvement in chest imaging and the need for additional interventions on the infected space.
Eligibility
Inclusion Criteria2
- Patients with complicated parapneumonic pleural effusion and empyema requiring chest tube placement as standard of care for inpatient management of their pleural space infection with or without intrapleural tissue plasminogen activator and deoxyribonuclease therapy
- Age > 18 years old.
Exclusion Criteria6
- Patients who have surgical tubes that can't accommodate a three-way stopcock.
- Study subject has any disease or condition that interferes with the safe completion of the study.
- Inability to provide informed consent.
- Inability to undergo a chest X-ray.
- If the managing clinician believes the chest tube will be placed for less than 24 hours.
- Patients with an indwelling pleural catheter (IPC)
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Interventions
sterile saline 20 mL flushed into their catheter by trained nurses or study team members every 6 ± 2 hours
Locations(5)
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NCT06427538