RecruitingNot ApplicableNCT06787885

Evaluation of Efficacy and Safety Parameters of Different Antibiotics Regimens for Management of Empyema


Sponsor

Fayoum University

Enrollment

90 participants

Start Date

May 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the impact of using different antibiotic regimens including single and combined agents as the empirical therapy and evaluate the clinical outcomes regarding safety, efficacy, and pharmacodynamics parameters.


Eligibility

Inclusion Criteria1

  • Confirmed Diagnosis of Empyema: Patients with a clinical and radiological diagnosis of

Exclusion Criteria2

  • - Hypersensitivity or Allergy to the selected antibiotic: Patients with a known history of hypersensitivity or allergic reactions to used antibiotics.
  • - Pregnancy and Lactation

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Interventions

DRUGLevofloxacin + clindamycin

Group 1

DRUGLevofloxacin + cefipime

Group 2

DRUGMoxifloxacin + meronam

Group 3


Locations(1)

Fayoum University hospital

Al Fayyum, Faiyum Governorate, Egypt

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NCT06787885


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