Bioavailability and Bioactivity of Orange Polyphenols
Bioavailability and Bioactivity of Orange Polyphenols on Gut Health
University of Ulster
20 participants
Apr 26, 2024
INTERVENTIONAL
Conditions
Summary
This study will provide a greater insight into the relationship between orange consumption and health (particularly gut health) and could be used to help with the development of novel food products. Oranges are a rich source of (poly)phenols, and although the advantages of a (poly)phenol-rich diet are well-established, the bioavailability and bioactivity of orange (poly)phenols in the context of human digestion are poorly understood. This study will address this gap in research.
Eligibility
Inclusion Criteria13
- Adult with an ileostomy, ≥1.5-years post-operative
- Aged 18-75 years at recruitment
- Not pregnant / lactating
- No learning or other disabilities
- Not currently taking antibiotics
- Not currently taking plant-based dietary supplements
- Not currently taking any prescribed medications that would prevent overnight fasting
- Aged 18-75 years at recruitment
- Not pregnant / lactating
- No learning or other disabilities
- Not currently taking antibiotics
- Not currently taking plant-based dietary supplements
- Not currently taking any prescribed medications that would prevent overnight fasting
Exclusion Criteria15
- Adults \<18 or \>75 years at recruitment
- Ileostomy, \<1.5 years post-operative
- Pregnant/lactating females
- Adults with learning or other disabilities
- Citrus fruit (orange) allergy or sensitivity
- Currently taking antibiotics
- Currently taking plant-based dietary supplements
- Currently taking any prescribed medications that would prevent overnight fasting
- Adults \<18 or \>70 years at recruitment
- Pregnant/lactating females
- Adults with learning or other disabilities
- Citrus fruit (orange) allergy or sensitivity
- Currently taking antibiotics
- Currently taking plant-based dietary supplements
- Currently taking any prescribed medications that would prevent overnight fasting
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Acute intervention in populations with and without colon
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06430138