RecruitingNot ApplicableNCT06434194

Serrantor OCT Study

Serranator OCT: Understanding the Mechanism of Action of Serration Angioplasty by Serranator Versus Conventional Balloon Angioplasty for below-the Knee (BTK) Artery Disease Using Optical Coherence Tomography (OCT)


Sponsor

Cagent Vascular LLC

Enrollment

60 participants

Start Date

Oct 31, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

TA prospective randomized control trial to evaluate the serration angioplasty effect in BTK arteries with varying degrees of calcified plaque.


Eligibility

Min Age: 19 Years

Inclusion Criteria3

  • Rutherford clinical category 4-6 of the target limb
  • Age of subjects is \>18 years old
  • Patients has given informed consent to participate in this study

Exclusion Criteria4

  • De novo or restenotic (without prior stent) stenosis (≥70%) or occlusion
  • Target lesion is in the BTK arteries, including below the knee popliteal, tibioperoneal trunk, tibial, peroneal, and pedal arteries.
  • Angiographic visual estimated reference vessel diameter is between 2.0 and 5.0 mm.
  • Lesion length less than 220 mm

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Interventions

DRUGPTA (Standard of Care)

A percutaneous transluminal angioplasty catheter will be used to treat the target lesion.

DEVICESerranator PTA Serration Catheter

The Serranator PTA Serration Balloon Catheter is an over-the-wire balloon dilatation catheter designed to perform percutaneous transluminal angioplasty (PTA) for peripheral indications.


Locations(2)

Columbia University

New York, New York, United States

Weill Cornell Medical

New York, New York, United States

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NCT06434194


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