Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis

This study tests whether cold atmospheric plasma — a type of ionized gas delivered through an endoscope — can treat small polyps in the small intestine (duodenum) in patients with Familial Adenomatous Polyposis (FAP), a genetic condition that causes many polyps to grow in the digestive tract. **You may be eligible if...** - You have a confirmed diagnosis of FAP - You have duodenal polyps that have been classified as Spigelman stage III (a moderate level of polyp burden) - Your polyps are smaller than 10 mm - You are able and willing to provide written informed consent **You may NOT be eligible if...** - Your polyps appear suspicious for high-grade cell changes or cancer - You are pregnant or breastfeeding - You have serious medical illnesses with a life expectancy under 1 year - You have a severe blood clotting disorder - Your intestine has inflammation, scarring, or narrowing that prevents the procedure Talk to your doctor to see if this trial is right for you.