RecruitingNot ApplicableNCT06436508

The Investigation of the Impact of Early Mobilization on the Outcome in Patients With Aneurysmal Subarachnoid Hemorrhage.

The Investigation of the Impact of Early Mobilization on the Outcome, the Appearance of Early Ischemic Damage, the Functional Status, and the Length of Intensive Care Treatment in Patients With Aneurysmal Subarachnoid Hemorrhage.


Sponsor

University of Pecs

Enrollment

50 participants

Start Date

Jun 14, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of the randomized clinical trial is to examine the effect of early mobilization on primary and secondary outcomes in patients with subarachnoid hemorrhage caused by aneurysm rupture. Researchers will compare early mobiliziation vs. standrad bed rest care.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Inclusion Criteria9

  • Age \>18 ys
  • Premorbid modified Rankin Scale score of 0-2
  • WFNS I-IV at enrollment
  • Aneurysm occlusion has occurred through open or endovascular means
  • Minimum 24 hours elapsed after aneurysm occlusion
  • The patient has not received thrombolytic therapy
  • Vital parameters are appropriate (mean arterial pressure \[MAP\] \>80 or \>110 mm Hg)
  • Signed patient information and consent form
  • Enrollment occurs within 72 hours following ictus

Exclusion Criteria5

  • Age under 18 years
  • Traumatic subarachnoid hemorrhage
  • Incapacitated or limited capacity for action before ictus
  • Confirmed pregnancy
  • Aneurysm multiplicity (unless all aneurysms are treated)

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Interventions

BEHAVIORALEarly mobilization protocol

* Step 1 - Day 1: Bed rest, elevation of the head end to 30° * Step 2 - Day 2: Bed rest, elevation of the head end to 60° * Step 3 - Day 3: Bed rest, elevation of the head end to 80° * Step 4 - Day 4: Sitting on the edge of the bed * Step 5 - Day 5: Sitting in a chair, standing up * Step 6 - Day 6: Walking with or without assistance * Step 7 - Day 7: Walking with or without assistance from today

BEHAVIORALStandard care

During standard care, early mobilization does not take place in the intensive care unit; the patient receives only standard supportive care in bed rest.


Locations(3)

University of Pecs

Pécs, Baranya, Hungary

Central Hospital of B.A.Z. County

Miskolc, BAZ, Hungary

National Institute of Mental Health, Neurology, and Neurosurgery

Budapest, Hungary

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NCT06436508


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