RecruitingNCT06439576

Real World Evidence in China: Faricimab Use in Diabetic Macular Edema, Retinal Vein Occlusion, and Neovascular Age-Related Macular Degeneration (The Farseeing Study)

China Faricimab Real World Evidence: Evaluation of Faricimab Effectiveness, Safety and Treatment Pattern, in Diabetic Macular Edema, Retinal Vein Occlusion and Neovascular Age-Related Macular Degeneration: The Farseeing Study


Sponsor

Hoffmann-La Roche

Enrollment

1,000 participants

Start Date

May 9, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The Farseeing Study will explore long-term effectiveness, safety, and treatment patterns among patients being treated with faricimab in real-world, routine clinical practice in China. It is a primary data collection, non-interventional, prospective and retrospective, multi-center study designed to collect real-world, long-term data to gain clinical evidence on faricimab, by observing cohorts of patients with neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) who are receiving treatment with faricimab.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Have signed the informed consent
  • Female and male Chinese patients, who had been diagnosed with nAMD, DME, or RVO by CFP, OCT, FFA, ICGA, or OCTA
  • ≥50 years old for patients with nAMD, ≥18 years old both for patients with DME and RVO, at the time of signing informed consent (or the first administration of faricimab, whichever occurs first)
  • Patients for whom the decision to receive treatment with faricimab is made prior to and independent from study participation
  • Patients have received at least one faricimab treatment (the first dose) in the study eye

Exclusion Criteria6

  • Patients not receiving treatment for nAMD/DME/RVO with faricimab according to the standard of care and in line with the current summary of product characteristics (SPC) / labeling in China
  • Active ocular inflammation or suspected / active ocular infection in either eye
  • Received any other anti-VEGF treatment after faricimab
  • Received any steroid treatment within 6 months (180 days) before the first faricimab treatment in the study eye
  • Any participation in any other clinical trials currently
  • Patients could not provide the clinical data (visual acuity and OCT images) within 2 weeks (14 days) before receiving the initial faricimab injection

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Interventions

DRUGFaricimab

The dosing and treatment duration of the studied medicinal product is at the discretion of the physician in accordance with clinical practice and labeling in China.


Locations(41)

Joint Shantou International Eye Center

Shantou, Guangdong, China

The First Affiliated Hospital of Henan UN of Science and Technology

Luoyang, Henan, China

Taihe Hospital of Shiyan

Shiyan, Hubei, China

Xuzhou No.1 Peoples Hospital

Xuzhou, Jiangsu, China

Fushun Eye Hospital

Fushun, Liaoning, China

Panjin Central Hospital

Panjin, Liaoning, China

The First Hospital of China Medical University

Shenyang, Liaoning, China

Affiliated Hospital of Shandong Second Medical University

Weifang, Shandong, China

Shanghai General Hospital

Shanghai, Shanghai Municipality, China

The First People's Hospital of Chengdu

Chengdu, Sichuan, China

The First People's Hospital of Kashgar

Kashgar, Xinjiang Uygur, China

The First People's Hospital of Yunnan Province

Kunming, Yun'nan, China

Jinhua municipal central hospital

Jinhua, Zhejiang, China

Peking University People's Hospital

Beijing, China

Sichuan Provincial People's Hospital

Chengdu, China

People's Hospital of Dingzhou

Dingzhou, China

Dongyang People's Hospital

Dongyang, China

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou, China

Guizhou Provincial People's Hospital

Guiyang, China

Eye Hospital of Shandong First Medical University

Jinan, China

The First Affiliated Hospital of Lanzhou University

Lanzhou, China

The Affiliated Hospital of Southwest Medical University, Zhongshan Campus

Luzhou, China

Jiangsu Province Hospital (the First Affiliated Hospital With Nanjing Medical University)

Nanjing, China

The People?s Hospital of Guangxi Zhuang Autonomous Region

Nanning, China

Qingdao Eye Hospital of Shandong First Medical University

Qingdao, China

Ruijin Hospital Shanghai Jiaotong University School of Medicine

Shanghai, China

Shanghai Tenth People's Hospital

Shanghai, China

Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, China

Shanghai Zhoupu Hospital

Shanghai, China

Shenyang Fourth People's Hospital

Shenyang, China

Shenzhen Eye Hospital

Shenzhen, China

Hebei People's Hospital

Shijiazhuang, China

Shanxi Bethune Hospital

Taiyuan, China

Tianjin Eye Hospital

Tianjin, China

Eye Hospital, Wenzhou Medical University

Wenzhou, China

Xiehe Hospital, Tongji Medical College Huazhong University of Science & Technology

Wuhan, China

Tongji Hospital Tongji Medical College Huazhong University of Science and Technology

Wuhan, China

Xiamen Eye Center Of Xiamen University

Xiamen, China

Hebei Eye Hospital

Xingtai, China

Henan Provincial Eye Hosptial

Zhengzhou, China

Affiliated Hospital of Zunyi Medical University

Zunyi, China

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