RecruitingNCT06439992

Beta Amyloid PET Imaging for Alzheimer Disease With [18F]-Fluselenamyl

Beta Amyloid PET Imaging for Alzheimer Disease: [18F]-Fluselenamyl (Alternative Vehicle) Comparison With [11C]-PIB (FSA-PIB AD)


Sponsor

Washington University School of Medicine

Enrollment

60 participants

Start Date

Nov 7, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this research study is to determine the safety of a radiotracer 18F-Fluselenamyl using positron emission tomography (PET) imaging.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests a new radioactive imaging agent called [18F]-Fluselenamyl that can detect beta-amyloid plaques in the brain — the protein build-up associated with Alzheimer's disease. Researchers will compare it to an existing approved imaging agent to see how well it works. **You may be eligible if...** - You are 18 years old or older, of any race or gender - You are either a healthy volunteer or someone with Alzheimer's disease **You may NOT be eligible if...** - You have a known allergy to the imaging agents used in this study - You are unable to provide consent or cooperate with the scanning procedure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUG18F-Fluselenamyl

Participants will receive a single intravenous bolus injection of 10 mCi ± 20% of the investigational radiotracer 18F-Fluselenamyl and will undergo an 18F-Fluselenamyl PET/CT scan of the head and neck.


Locations(1)

Washington University School of Medicine

St Louis, Missouri, United States

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NCT06439992


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