Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke
Transcranial Electrical Stimulation in Stroke EaRly After Onset Clinical Trial 2
University of California, Los Angeles
120 participants
Jul 15, 2025
INTERVENTIONAL
Conditions
Summary
Many patients with acute ischemic stroke are ineligible for currently available standard treatments (clot-busting medication, also known as intravenous thrombolytic or mechanical removal of a clot), and many are non-responders, resulting in a low rate of excellent outcomes, which necessitates the development of novel therapies. In this study, investigators are testing a new treatment in which a weak electrical current will be applied via scalp electrodes to increase collateral blood flow to the brain and rescue the brain tissue at risk of injury. The primary aim is to find an optimal dose of this therapy that is both adequately safe and effective on imaging markers of brain tissue rescue.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
The active study treatment involves delivering a weak form of electrical stimulation via 5 small electrodes to the brain tissue at risk of infarction.
Sham patients will have cap and electrodes in place, but no stimulation will be delivered.
Locations(3)
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NCT06440707