A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B

This study tests the safety and effectiveness of a combination treatment using two drugs — AD-227A and AD-227B — for people with essential hypertension (high blood pressure with no identifiable underlying cause). The goal is to see if the combination controls blood pressure better than current options. **You may be eligible if...** - You have been diagnosed with essential (primary) hypertension — high blood pressure without a known secondary cause - You meet other inclusion criteria as determined by the study team **You may NOT be eligible if...** - You have secondary hypertension (high blood pressure caused by another medical condition, such as kidney disease or a hormone disorder) - You meet other exclusion criteria as determined by the study team Talk to your doctor to see if this trial is right for you.