One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term
One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term: A Longitudinal Cohort Study
Fujian Medical University
400 participants
Jun 1, 2023
OBSERVATIONAL
Conditions
Summary
The purpose of this study was to investigate the one-year trajectory of cognitive change in elderly patients with depression, to explore the transfer characteristics and transfer rules of various states of cognitive impairment in patients, to predict the relevant risk factors of cognitive decline, and to find possible influencing factors affecting state change, so as to provide a theoretical basis and reference for subsequent targeted intervention research on geriatric depression.
Eligibility
Inclusion Criteria3
- meeting the criteria for major depression in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
- age at first onset ≥60 years
- Informed consent
Exclusion Criteria4
- Relevant past history affecting cognitive function: various types of stroke, traumatic brain injury, severe brain atrophy, mental abnormalities
- Perennial alcohol addiction, or long-term use of various drugs that affect mental state
- Survival time of malignant tumors and tumors
- Patients with language, vision, and hearing impairments
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06447428