RecruitingNCT06447428

One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term

One-Year Trajectory of Cognitive Changes in Patients With Late-life Depression in the Short Term: A Longitudinal Cohort Study

Sponsor

Fujian Medical University

Enrollment

400 participants

Start Date

Jun 1, 2023

Study Type

OBSERVATIONAL

Conditions

Late Life Depression

Summary

The purpose of this study was to investigate the one-year trajectory of cognitive change in elderly patients with depression, to explore the transfer characteristics and transfer rules of various states of cognitive impairment in patients, to predict the relevant risk factors of cognitive decline, and to find possible influencing factors affecting state change, so as to provide a theoretical basis and reference for subsequent targeted intervention research on geriatric depression.

Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study follows older adults with depression over one year to track how their thinking and memory change over time. Researchers want to understand whether late-life depression affects cognitive function and how it progresses. **You may be eligible if...** - You meet the clinical diagnosis of major depression - Your depression first began at age 60 or older - You are willing to give informed consent to participate **You may NOT be eligible if...** - You have a history of stroke, brain injury, or significant brain atrophy - You have a long-term alcohol addiction or take medications that affect your mental state - You have a terminal cancer diagnosis with short life expectancy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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