Local Liver Treatment for Multi-organ Colorectal Cancer Metastases

This study investigates whether adding local liver treatment (such as ablation or embolization) to systemic chemotherapy improves survival in patients with colorectal cancer that has spread to both the liver and other organs. **You may be eligible if...** - You are between 18 and 80 years old - You have colorectal cancer with confirmed spread to both the liver and at least one other site (such as lungs or lymph nodes) - Your primary colorectal tumor has been or can be surgically removed - You are receiving first- or second-line chemotherapy **You may NOT be eligible if...** - Your extrahepatic (outside the liver) metastases are not stable or controllable - You have received more than two lines of chemotherapy Talk to your doctor to see if this trial is right for you.