RecruitingNot ApplicableNCT06453746

Effectiveness of Non-pharmacological Interventions for Dementia Prevention in Elderly Patients With Mild Cognitive Impairment

Effectiveness of Dementia Prevention in Elderly Patients With Mild Cognitive Impairment at Nhân dân Gia Định Hospital, Hồ Chí Minh City

Sponsor

Gia Dinh People Hospital

Enrollment

192 participants

Start Date

Aug 26, 2024

Study Type

INTERVENTIONAL

Conditions

Mild Cognitive Impairment Dementia Prevention

Summary

The aims of this study is to evaluate the effectiveness of non-pharmacological interventions program in preventing progression from mild cognitive impairment to dementia in patients with mild cognitive impairment in the short term, at Nhân dân Gia Định Hospital, Hồ Chí Minh City.

Eligibility

Min Age: 60 Years

Inclusion Criteria10

Subjects diagnosed with mild cognitive impairment:
Cognitive complaints from the subject or a family member.
Report a decline in cognitive function compared to the subject's previous ability over the past year OR
Evidence from clinical assessment, specifically here is MMSE screening with results of 24-29 points.
Subjects did not suffer major impacts from cognitive complaints on daily life.
No prior diagnosis of dementia.
Ensure transportation from living location to hospital.
Have at least one relative or caregiver who can supervise the subject's daily activities.
Stable chronic underlying conditions (diabetes, hypertension).
Consent to participate in the study.

Exclusion Criteria9

Don't know Vietnamese writing.
Audio-visual ability does not meet the requirements of assessment tests and prevention programs.
Systemic diseases are contraindications/ restriction to participation in programs and/or cause secondary cognitive impairment (traumatic brain injury, stroke, brain tumor, parkinsonism, epilepsy, acute coronary artery disease, acute myocardial infarction, bone fractures...).
The assessment score on the Geriatric Depression Scale (GDS-15) is ≥ 5 points.
Diagnosed with other mental disorders that may limit the ability to understand, communicate and work in groups (schizophrenia, mania, bipolar disorder, dissociative disorder, generalized anxiety disorder).
Currently participating in another research program on dementia prevention or a research program on medication to prevent dementia within the last 3 months.
Taking medications that may affect cognitive function, such as benzodiazepines, hypnotics, and antipsychotics.
Alcohol abuse: drinking alcohol daily or consuming more than 14 units of alcohol per week (equivalent to 10 grams of ethanol, as defined by the Ministry of Health); diagnosed with alcohol dependence or currently being treated for mental illness due to alcohol dependence.
Do not agree to participate in the study.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERHome-based cognitive training exercises

The subjects received (i) education on lifestyle modification, (ii) home-based cognitive training exercises with physiotherapist/ physiatrist contact when needed and (iii) a physical training exercises conducted at hospital under the supervision of physiotherapist/ physiatrist (3 weekly session for 12 weeks). This arm has a duration of 12 weeks.

OTHERSupervised cognitive training exercises

The subjects received (i) education on lifestyle modification, (ii) supervised cognitive training exercises at hospital (1 weekly session for 12 weeks) and (iii) a physical training exercises conducted in a hospital under the supervision of physiotherapist/ physiatrist (3 weekly session for 12 weeks). This arm has a duration of 12 weeks.