RecruitingNot ApplicableNCT06453980

Multimodal Investigation of Neural Plasticity

Multimodal Investigation of Neural Plasticity Induced by Non-invasive Brain Stimulation


Sponsor

University of Michigan

Enrollment

80 participants

Start Date

May 13, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study will evaluate the effects of a form of non-invasive brain stimulation on brain functioning and memory in cognitively intact older adults (healthy controls, HC) and in those with mild cognitive impairment (MCI).


Eligibility

Min Age: 60 Years

Inclusion Criteria3

  • Normal cognition for HC and diagnosis of Mild Cognitive Impairment (MCI) for MCI participants
  • Right-handedness
  • Magnetic resonance compatible, criteria that also apply for high definition transcranial direct current stimulation (HD-tDCS; e.g., absence of metallic or electronic implants in the upper body or head)

Exclusion Criteria4

  • History of other contributing neurological or medical conditions known to affect cognitive functioning
  • Significant mental illness
  • Sensory impairments that limit ability to participate
  • History of alcohol or drug abuse/dependence

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Interventions

DEVICEsham tDCS

Participants will receive sham (placebo) HD-tDCS for 20 minutes, for 1 session.

DEVICEactive tDCS

Participants will receive HD-tDCS at 3 milliAmp for 20 minutes, for 1 session.


Locations(1)

University of Michigan

Ann Arbor, Michigan, United States

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NCT06453980


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