GP Plus Adebrelimab Versus GP Neoadjuvant Chemotherapy for Nasopharyngeal Carcinoma

This study is testing whether adding an immunotherapy drug called adebrelimab to standard chemotherapy (gemcitabine + cisplatin) before surgery is more effective than chemotherapy alone for people with a specific type of throat cancer called nasopharyngeal carcinoma. **You may be eligible if...** - You are between 18 and 65 years old - You have been diagnosed with nasopharyngeal carcinoma (a cancer at the back of the nasal passage) confirmed by biopsy - Your cancer is at an advanced local stage (stage T4N0-1 or T1-4N2-3, no distant spread) - You have not received any prior cancer treatment - You are in good general health **You may NOT be eligible if...** - Your cancer has spread to distant organs - You have already received cancer treatment - You are pregnant - Your organ function (blood, liver, kidney) does not meet the required levels Talk to your doctor to see if this trial is right for you.