RecruitingNot ApplicableNCT06458062

Pocket Colposcopy Using CARE Algorithm

Development and Validation of an Artificial-Intelligence-enabled Portable Colposcopy Device for Optimizing Triage Alternatives for HPV-based Cervical Cancer Screening


Sponsor

Duke University

Enrollment

1,079 participants

Start Date

Feb 15, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The Pocket colposcope has 510k FDA clearance and has been successfully used in \~2500 unique patients globally in Duke and non-Duke protocols to date. 1054 women who are HPV(+) and planned to undergo treatment at four Ministry of Health-supported outpatient clinics in Kisumu County will be recruited to the study. After providing informed consent, participants will be proceed with colposcopy using the POCKET colposcope.


Eligibility

Sex: FEMALEMin Age: 25 Years

Inclusion Criteria3

  • Age ≥ 30 years old and ≤ 64 years old; or Age ≥ 25 years old if women living with HIV (WLWH)
  • Sex: Female
  • Positive HPV test within past 6 months

Exclusion Criteria6

  • Pregnant women (cannot perform a cervical biopsy on a patient who is pregnant unless absolutely indicated)
  • Women with a negative HPV test within the past 9 months
  • Patients incapable of giving informed consent
  • Women with a history of cervical cancer
  • Pelvic exam concerning for cervical cancer or cervical infection
  • History of hysterectomy

Interventions

DEVICEPocket Colposcope

Each patient will receive treatment in order to prevent cervical cancer


Locations(1)

Kenya Medical Research Institute

Nairobi, Kenya

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NCT06458062


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