Speech Motor Learning and Retention (Master Protocol)
Sensorimotor Basis of Speech Motor Learning and Retention
Yale University
330 participants
Oct 1, 2024
INTERVENTIONAL
Conditions
Summary
The overall goal of this research is to test a new model of speech motor learning, whose central hypothesis is that learning and retention are associated with plasticity not only in motor areas of the brain but in auditory and somatosensory regions as well.
Eligibility
Inclusion Criteria4
- Fluent English speakers
- Right-handed
- Normal hearing
- No speech disorder or reading disability
Exclusion Criteria12
- Cardiac pacemaker
- Aneurysm clip
- Heart or Vascular clip
- Prosthetic valve
- Metal implants
- Metal in brain, skull, or spinal cord
- Implanted neurostimulator
- Medication infusion device
- Cochlear implant or tinnitus (ringing in ears)
- Personal and/or family history of epilepsy or other neurological disorders or history of head concussion
- Psychoactive medications
- Pregnancy
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Interventions
cTBS stimulation will be applied to different areas of the brain following learning. Stimulation will take place following learning in order to block motor memory retention.
Auditory adaptation in speech
TMS will be delivered 10 times in each motor evoked potentials (MEP) recording block.
To assess functional connectivity patterns between regions that predict learning.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06467292